NatPROB release the symposium: Natural Products as Sources of Therapeutic Agents for Oral Diseases Prevention

90^th General Session & Exhibition of the IADR - International Association for Dental Research

June 20-23, 2012 in Iguaçu Falls, Brazil

Symposium Program

Title of Symposium

“Natural Products as Sources of Therapeutic Agents for Oral Diseases Prevention”

Date - Wednesday, June, 20, 2012: 4:00 a.m.-5:30 p.m.

Location – Bourbon Hotel, Iguaçu Falls, Brazil

Description

Natural products and their derivatives offers a rich source of structurally diverse and wide range of biologically active substances which could be useful for development of alternative or adjunctive agents to prevent or treat oral infectious diseases, such as dental caries and periodontal diseases. However, research using natural products for oral diseases prevention is challenging owing to complex chemistry and isolation procedures of natural products. The confluence of new isolation/analytical technologies with advances in ‘omics’-based knowledge and in (bio)synthetic chemistry will certainly enhance future investigations of using natural products in oral research. This symposium provides an overview of the current status, challenges, scientific methodologies, and prospects for use of naturally occurring compounds in the development of novel therapies against oral diseases.

Organizers

§  P.L. Rosalen (Professor, Department of Pharmacology, Piracicaba Dental School, State University of Campinas – UNICAMP, Brazil);

§  Bruno Bueno-Silva (Ph.D. student, Department of Pharmacology, Piracicaba Dental School, State University of Campinas – UNICAMP, Brazil);

§  H. Koo (Associate Professor, Center for Oral Biology and Department of Microbiology& Immunology, University of Rochester Medical Center, NY, USA); and

§  J.G. Jeon (Professor, School of Dentistry of Chonbuk National University, Chonbuk, Republic of Korea)

Chair: P. L. Rosalen

Alternate Chair: J.G. Jeon

Speakers and topics:

      Key Note: Natural Products Sources of Therapeutic Agents for Oral Diseases Prevention

P.L. Rosalen, Full professor in Pharmacology, Graduate Program in Dentistry, Piracicaba Dental School, State University of Campinas, UNICAMP

(Speaker Note: Dr. Rosalen is a well-recognized expert in bioprospecting research of molecules in natural products in oral disease, with over 70 peer-reviewed publications)

       Natural Products - A Continuing Source of Novel Biomolecules with Therapeutic Potential  

G.M.Cragg, NIH Special Volunteer, ex-Chief of Natural Products Branch, Developmental Therapeutics Program, National Cancer Institute, NCI-Frederick, NIH, Bethesda, MD, USA.

(Speaker Note: Dr. Cragg is a well-recognized world-expert in natural product research, current NIH Special Volunteer and ex-chief of the Natural Products Branch at the National Cancer Institute, National Institutes of Health, with over 150 peer-reviewed publications)

    Toxicology and Pharmacology of Natural Products

J.B. CALIXTO, Professor, Department of Pharmacology, Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC, Brazil.

(Speaker Note: Dr. Calixto is a world-authority in research on toxicology and pharmacological effects of natural products using both in vitro and in vivo models, with over 250 peer-reviewed publications)

     Approaches for Isolation of Biomolecules from Complex Mixtures

N. VORSA, Professor, Department of Plant Biology and Plant Pathology, and Director of Philip E. Marucci Center for Blueberry and Cranberry Research at Rutgers University, Chatsworth, NJ, USA.

(Speaker Note: Dr. Vorsa is a world-authority in cranberry research with expertise in the field of plant genetics and chemistry. His pioneering work isolated several bioactives from genetically characterized cranberries, and led to discovery of novel molecules against infectious diseases, including biofilms-related oral diseases. Dr. Vorsa has more than 100 peer-reviewed publications)

       Natural Products in Dental Research: Current knowledge and future perspective
H. KOO, Associate Professor, Center for Oral Biology and Department of Microbiology & Immunology, University of Rochester Medical Center, Rochester, NY, USA.

(Speaker Note: Dr. Koo is a well-recognized expert and the leading dental scientist in the field of natural products research on biofilm related oral diseases, particularly dental caries, using both in vitro and in vivo models, with over 70 peer-reviewed publications).

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