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Pictures of Symposium

Check the pictures of our symposium about Natural Products in 90th IADR, in Iguaçu Falls.

The speakers: Dr. Vorsa, Dr. Cragg, Dr. Calixto, Dr. Koo and Dr. Rosalen (from left to right).

Current members of NatPROB: Dr. Koo, Dr. Rosalen, Dr. Bueno-Silva and Dr. Jeon (from left to right)

The Iguaçu Falss !!

                                                                         confraternization...

Thanks to everyone who attended the Symposium and we look forward to see you again in the next NatPROB event.

NatPROB release the symposium: Natural Products as Sources of Therapeutic Agents for Oral Diseases Prevention

90^th General Session & Exhibition of the IADR - International Association for Dental Research

June 20-23, 2012 in Iguaçu Falls, Brazil

Symposium Program

Title of Symposium

“Natural Products as Sources of Therapeutic Agents for Oral Diseases Prevention”

Date - Wednesday, June, 20, 2012: 4:00 a.m.-5:30 p.m.

Location – Bourbon Hotel, Iguaçu Falls, Brazil

Description

Natural products and their derivatives offers a rich source of structurally diverse and wide range of biologically active substances which could be useful for development of alternative or adjunctive agents to prevent or treat oral infectious diseases, such as dental caries and periodontal diseases. However, research using natural products for oral diseases prevention is challenging owing to complex chemistry and isolation procedures of natural products. The confluence of new isolation/analytical technologies with advances in ‘omics’-based knowledge and in (bio)synthetic chemistry will certainly enhance future investigations of using natural products in oral research. This symposium provides an overview of the current status, challenges, scientific methodologies, and prospects for use of naturally occurring compounds in the development of novel therapies against oral diseases.

Organizers

§  P.L. Rosalen (Professor, Department of Pharmacology, Piracicaba Dental School, State University of Campinas – UNICAMP, Brazil);

§  Bruno Bueno-Silva (Ph.D. student, Department of Pharmacology, Piracicaba Dental School, State University of Campinas – UNICAMP, Brazil);

§  H. Koo (Associate Professor, Center for Oral Biology and Department of Microbiology& Immunology, University of Rochester Medical Center, NY, USA); and

§  J.G. Jeon (Professor, School of Dentistry of Chonbuk National University, Chonbuk, Republic of Korea)

Chair: P. L. Rosalen

Alternate Chair: J.G. Jeon

Speakers and topics:

      Key Note: Natural Products Sources of Therapeutic Agents for Oral Diseases Prevention

P.L. Rosalen, Full professor in Pharmacology, Graduate Program in Dentistry, Piracicaba Dental School, State University of Campinas, UNICAMP

(Speaker Note: Dr. Rosalen is a well-recognized expert in bioprospecting research of molecules in natural products in oral disease, with over 70 peer-reviewed publications)

       Natural Products - A Continuing Source of Novel Biomolecules with Therapeutic Potential  

G.M.Cragg, NIH Special Volunteer, ex-Chief of Natural Products Branch, Developmental Therapeutics Program, National Cancer Institute, NCI-Frederick, NIH, Bethesda, MD, USA.

(Speaker Note: Dr. Cragg is a well-recognized world-expert in natural product research, current NIH Special Volunteer and ex-chief of the Natural Products Branch at the National Cancer Institute, National Institutes of Health, with over 150 peer-reviewed publications)

    Toxicology and Pharmacology of Natural Products

J.B. CALIXTO, Professor, Department of Pharmacology, Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC, Brazil.

(Speaker Note: Dr. Calixto is a world-authority in research on toxicology and pharmacological effects of natural products using both in vitro and in vivo models, with over 250 peer-reviewed publications)

     Approaches for Isolation of Biomolecules from Complex Mixtures

N. VORSA, Professor, Department of Plant Biology and Plant Pathology, and Director of Philip E. Marucci Center for Blueberry and Cranberry Research at Rutgers University, Chatsworth, NJ, USA.

(Speaker Note: Dr. Vorsa is a world-authority in cranberry research with expertise in the field of plant genetics and chemistry. His pioneering work isolated several bioactives from genetically characterized cranberries, and led to discovery of novel molecules against infectious diseases, including biofilms-related oral diseases. Dr. Vorsa has more than 100 peer-reviewed publications)

       Natural Products in Dental Research: Current knowledge and future perspective
H. KOO, Associate Professor, Center for Oral Biology and Department of Microbiology & Immunology, University of Rochester Medical Center, Rochester, NY, USA.

(Speaker Note: Dr. Koo is a well-recognized expert and the leading dental scientist in the field of natural products research on biofilm related oral diseases, particularly dental caries, using both in vitro and in vivo models, with over 70 peer-reviewed publications).

Sponsored  by:

  

NatPROB – Release the new publication at Caries Research journal (May 2011)

The researcher leaders of NatPROB received from the outstanding journal Caries Research’s editor the acceptance of their manuscript regarding to Natural Products in dental research.

This paper reflects the expertise and philosophy of the group of researchers that created NatPROB aligned with a policy of awareness of scientific and for a sustainable environmental.

Please, have a pleasant and productive reading of the

Natural Products in Caries Research: Current (Limited) Knowledge, Challenges and Future Perspective.

Authors: Jeon JG, Rosalen PL, Falsetta ML, Koo H.

Caries Res. 2011 May 12;45(3):243-263. (DOI: 10.1159/000327250),

and you may access the full text at: http://content.karger.com/produktedb/produkte.asp?DOI=000327250&typ=pdf

NatPROB presented 9 investigations and received 2 Hatton Awards at 2011's IADR, San Diego, California, USA

Investigators from NatPROB presented their researches at the 2011 (89^th) IADR General Session & Exhibition / AADR Annual Meeting / CADR Annual Meeting on March 16 through March 19, 2011 in San Diego Convention Center, CA, USA.

The NatPROB’s researchers and their teams presented nine paper including participation in the Hatton Award, one of the most prestigious competitions of the meeting. In this competition, NatPROB’s researches were the only group to receive two Hatton Awards, as followed:

- 1^st place in the Senior Category of IADR Hatton Award went to Abstract # 1825 Modulation of immunological synapse by antidepressants suppresses periodontal bone loss. L.S. BRANCO-DE-ALMEIDA, G.C.N. FRANCO, H.E. MACKLER, M. KAJIYA, X. HAN, P.L. ROSALEN, M.A. TAUBMAN, and T. KAWAI.

- Post-doctoral Category from AADR of Hatton Award went to Abstract # 1857 EPS-microcolony complexes modulate Streptococcus mutans survival-competitiveness within mixed-species biofilms. J. XIAO, M.I. KLEIN and H. KOO.

Please see below the list of NatPROB’s researches presented at the 89^th Annual Meeting of the IADR, San Diego, CA, USA, whose contents can be viewed at: http://iadr.confex.com/iadr/2011sandiego/webprogram/

Abstract # 19: Candida albicans interactions with Streptococcus mutans and apatitic surfaces. H. KOO¹, S. GREGOIRE¹, J. XIAO¹, B. SILVA¹, M. KLEIN¹, P.L. ROSALEN², R. BAUSERMAN¹, and R. WAUGH¹, ¹School of Medicine and Dentistry, University of Rochester, Rochester, NY, ²Piracicaba Dental School, University of Campinas State - Piracicaba, Piracicaba, SP, Brazil

Abstract # 55 Characterization of Streptococcus mutans proteome during biofilm development using MudPIT. M.I. KLEIN¹, J. XIAO¹, B. LU², J.R. YATES III², and H. KOO¹, ¹School of Medicine and Dentistry, University of Rochester, Rochester, NY, ²The Scripps Research Institute, La Jolla, CA

Abstract # 1469: Antimicrobial activity of fractions of Anadenanthera macrocarpa on mutans streptococci. R. YATSUDA¹, K.O. SILVA¹, É.P. SOUZA¹, J.C. DUARTE², M.A.M. SANTANA², G.C. MESSIAS¹, N.K.B. RIBEIRO¹, G.S. SANTOS¹, R.S.D.M. DÓREA¹, M.F. ANDRADE¹, V.S. MEIRELES¹, D.D. SAMPAIO¹, C.M.F. ANDRADE¹, L.M. MARQUES¹, P.L. ROSALEN³, and M.P. CRUZ¹, ¹Instituto Multidisciplinar em Saúde, Universidade Federal Da Bahia, Vitória da Conquista, Brazil, ²Universidade Federal Da Bahia, Vitória da Conquista, Brazil, ³Piracicaba Dental School, University of Campinas State - Piracicaba, Piracicaba, SP, Brazil

Abstract # 1825: Modulation of immunological synapse by antidepressants suppresses periodontal bone loss. L.S. BRANCO-DE-ALMEIDA¹, G.C.N. FRANCO², H.E. MACKLER³, M. KAJIYA³, X. HAN³, P.L. ROSALEN¹, M.A. TAUBMAN³, and T. KAWAI³, ¹Faculdade de Odontologia de Piracicaba, FOP/UNICAMP, Piracicaba SP, Brazil, ²University of Taubaté, Taubaté, Brazil, ³Department of Immunology, Forsyth Institute, Cambridge, MA

Abstract # 1857: EPS-microcolony complexes modulate Streptococcus mutans survival-competitiveness within mixed-species biofilms. J. XIAO, Dentistry, Center for Oral Biology, University of Rochester, Rochester, NY, M.I. KLEIN, School of Medicine and Dentistry, University of Rochester, Rochester, NY, and H. KOO, University of Rochester Medical Center, Rochester, NY

Abstract # 2649: Catecholamines increase the adhesion of Streptococcus mutans on orthodontic brackets. G.C.N. FRANCO¹, M.L. CASTRO², K. COGO¹, S.C. CORTELLI¹, A.C. ANDRADE¹, and P.L. ROSALEN³, ¹University of Taubaté, Taubaté, Brazil, ²Farmacologia, Universidade Estadual de Campinas, Piracicaba, Brazil, ³Piracicaba Dental School, University of Campinas State - Piracicaba, Piracicaba, SP, Brazil

Abstract # 2771: Effects of red propolis bioactive-fraction on S. mutans biofilms development. B.B. SILVA, Piracicaba Dental School, Piracicaba, Brazil, S.M. ALENCAR, "Luis de Queiroz" college of Agriculture, Piracicaba, Brazil, M. IKEGAKI, Federal university of Alfenas, Alfenas, Brazil, P.L. ROSALEN, Piracicaba Dental School, University of Campinas State - Piracicaba, Piracicaba, SP, Brazil, and H. KOO, School of Medicine and Dentistry, University of Rochester, Rochester, NY

Abstract # 2772: Influences of red propolis on S.mutans-transcriptome responses within biofilms. P.L. ROSALEN, Piracicaba Dental School, University of Campinas State - Piracicaba, Piracicaba, SP, Brazil, B.B. SILVA, Piracicaba Dental School, Piracicaba, Brazil, M. FALSETTA, University of Rochester School of Medicine and Dentistry, Rochester, NY, M. IKEGAKI, Federal university of Alfenas, Alfenas, Brazil, S.M. ALENCAR, "Luis de Queiroz" college of Agriculture, Piracicaba, Brazil, and H. KOO, School of Medicine and Dentistry, University of Rochester, Rochester, NY

Abstract # 3029: Transcriptional Responses of Streptococcus mutans Biofilm Cells to Novel Therapeutics. M.L. FALSETTA, M.I. KLEIN, and H. KOO, School of Medicine and Dentistry, University of Rochester, Rochester, NY

NatPROB presents at 2011's IADR, San Diego, California, USA

Investigators from NatPROB will present their researches at the 2011 IADR General Session & Exhibition / AADR Annual Meeting / CADR Annual Meeting on March 16 through March 19, 2011 in San Diego Convention Center, CA, USA (http://www.iadr.com/i4a/pages/index.cfm?pageid=3912).

The NatPROB’s researchers and their teams will present nine paper including participation in the Hatton Award, one of the most prestigious competitions of the meeting.

Soon we will publish the abstracts of the presentations.

NatPROB

WELCOME

Welcome to The Natural Product Research Group in Oral Biology's (NatPROB) official website.
It is now open and you are invited to navigate through all of our informations and publications.

NatPROB is a research group that was officially created in October 2010 with an objective of gathering three international institutions to research natural produts focusing oral health in a multidisciplinary way.